IndraLab

Statements


USP24 deubiquitinates BAX. 2 / 2
1 | 1

"In this study, several cancer-related proteins (Bax, p300, E2F4 and securin) have been proven to be substrates of ubiquitin-specific peptidase 24 (USP24), and relevance has been shown between USP24 and its substrates in samples from clinical lung cancer patients. |Knockdown of USP24 decreases Bax and p300 levels"

reach
"In agreement with previous reports indicating that USP24 may de-ubiquitinate the pro apoptotic BH3 protein BAX [31], we also observed a decrease in BAX protein levels in USP24 knockdown cells)."