IndraLab

Statements

USP9X activates Wnt. 5 / 6
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"In summary, these results indicate that USP9X stabilizes beta-catenin and activates Wnt and beta-catenin signal pathway to promote glioma cell proliferation and survival."
27783990
reach
"By evaluating signaling in U251 cells treated with a Wnt ligand, we found that USP9X knockdown partly blocked the activation of Wnt and beta- catenin pathway by regulating the stability of beta-catenin."
27783990
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"Down-regulation of USP9X also consistently inhibits the tumorigenicity of primary glioma cells in vivo.In summary, these results indicate that USP9X stabilizes beta-catenin and activates Wnt and beta-catenin signal pathway to promote glioma cell proliferation and survival."
27783990
reach
"Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors."
28808228
eidos
"USP9X enhances Wnt signaling through deubiquitinating Dv12 ."
36340031