IndraLab

Statements


COPS6 increases the amount of MYC. 2 / 2
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"More importantly, overexpression of CSN6 increased c-Myc protein level in Tespa1 HSCs but not in Tespa1 HSCs, indicating that CSN6 stabilizes c-Myc in the presence of Tespa1."

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"Compared with wt CSN6, which clearly decreased Fbxw7 expression and increased Myc expression in U2OS cells, the MPN-KQV CSN6 mutant lost these functions (XREF_SUPPLEMENTARY)."