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USP20 ubiquitinates TRAF6. 5 / 5
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"USP20 suppresses IL-1β- and Tax-induced NF-κB activation, by deubiquitinating TRAF6 and Tax, thus, inhibiting HTLV-1-transformed cell growth [132] ."
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"K63-linked poly-ubiquitination is significant for the activation of TRAF6, deubiquitinase A20, CYLD and USP20 have been reported to inhibit signal pathway transduction by removing the ubiquitination o[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"(3) As a scaffold protein, β-arrestin2 forms a ternary complex with TRAF6 and ubiquitin-specific protease 20 (USP20), promoting the ubiquitination of TRAF6 by USP20 [ 33 ]."
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"The knockout of β-arrestin2 or USP20 enhances the ubiquitination of TRAF6 without cumulative effect [ 21 ]."
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"The C-terminal of β-arrestin2 binds to TRAF6 after the activation of TLR4, preventing oligomerization and self-ubiquitination of TRAF6 to negatively regulate the activation of NFκB [ 33 , 56 ]. (2) Th[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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