IndraLab

Statements

RPS6 activates KCNH2. 5 / 5
| 4 1
reach
"One S6 T peptide activates hERG channels."
28273916
reach
"The apparently large size of the central cavity below the selectivity filter, and the positioning of the aromatic side chains of Y652 and F656 on S6 allow hERG to accommodate diverse drugs XREF_BIBR, XREF_BIBR."
27256139
sparser
"One S6 T peptide activates hERG channels."
28273916
reach
"In contrast to HCN channel inactivation, however, HERG inactivation is not mediated by a loose coupling of S4-S5 linker and S6 T but by conformational changes at the outer pore region."
22988442
reach
"The S6 residue HERG mutant Y652A and F656C largely reduced the blocking potency of HERG current."
17516459