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"Consecutive treatment of STZ-induced diabetic neuropathic pain rats with 50 mg/kg curcumin for 4 weeks decreased the number of pJNK immunoreactive cells that were colocalized with both GFAP and NF200 in the DRG (Figures 4(d) and 5(d), respectively)."

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"Furthermore, to investigate if curcumin could inhibit p-JNK activation in a similar way to the JNK inhibitor SP600125, we exposed BV2 microglial cells to 1 μg/ml LPS, 100 μg/ml curcumin, and 20 μM SP600125."

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"In a C6 orthotropic xenograft , curcumin suppressed the phosphorylated JNK1 and JNK2 levels , which decreased lipopolysaccharide-induced CCL2 production [ 49 ] ."

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"However, as shown in Figure XREF_FIG, the treatment of curcumin remarkably inhibited the phorsphorylation of JNK3 rather than JNK1 and 2."