IndraLab

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USP40 increases the amount of Claudin1. 2 / 2
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"MHCC97H cells with stable knockdown of USP40 were transfected with Claudin1 plasmid or vector, and western blotting showed that USP40 silencing reduced Claudin1 protein levels, which could be restored by overexpressing Claudin1 (Fig. 6A)."
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"Western blotting analysis of tumor tissues suggested that USP40 knockdown suppressed Claudin1 expression, and USP40 overexpression promoted Claudin1 expression (Fig. 7D, H), which was in accordance with the findings of in vitro experiments."
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