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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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USP49 inhibits cell growth. 3 / 3

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"As a result, overexpression of USP49 significantly inhibited cell growth of NSCLC cells."

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"USP49 was also reported to inhibit non-small cell lung cancer cell growth by suppressing PI3K/AKT signaling ."

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"In conclusion, we demonstrated that USP49 was functional in NSCLC cells, and inhibited NSCLC cell growth by suppressing PI3K and AKT signaling, suggesting that USP49 could be as a novel target for NSCLC therapy."

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Statements

USP49 inhibits cell growth. 3 / 3

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