IndraLab

Statements

UCHL3 decreases the amount of TDP1. 3 / 3
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reach
"Depletion of UCHL3 was sufficient to reduce TDP1 expression in rhabdomyosarcoma cells to levels comparable to control cells (XREF_FIG D, top) and led to hypersensitivity to the TOP1 poison CPT (XREF_FIG D, bottom)."
29898404
reach
"UCHL3 decreases the ubiquitination level of TDP1 leading to the inhibition of TDP1 degradation."
31967940
reach
"Depletion of UCHL3 in rhabdomyosarcoma cells reduced TDP1 levels and sensitized cells to TOP1 poisons."
29898404