IndraLab

Statements

2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile activates KCNH2. 2 / 2
| 2
reach
"Verapamil antagonized dofetilide block of HERG channels, which suggests that they may share a common binding site."
10325236
reach
"However loss of indicator brightness represents a weakness in this strategy as although the anticipated CTD shortening with nifedipine was seen, the opposite trend due to off-target hERG block by verapamil was missed even though this was detected in parallel patching studies."
28379974