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USP12 increases the amount of ISGs. 2 / 2

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"USP12 deficiency also significantly inhibited the expression of ISGs (ISG15, MX1, and IFIT1) in BMDMs and MEFs infected with a DNA or an RNA virus (Figs 1B and S2B)."

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"USP12 knockdown also reduced the expression of ISGs (ISG15, MX1, and IFIT1) in both the DNA and RNA virus infected-groups (Fig 2B)."

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USP12 increases the amount of ISGs. 2 / 2

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