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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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USP8 activates Cell Survival. 3 / 3

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"USP8 inhibition markedly reduced cell viability in gefitinib resistant and -sensitive NSCLC cells, but exhibited no observable effects on normal control cells (XREF_FIG)."

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"The silencing USP8 and docetaxel treatment reduced cell viability and migration and promoted apoptosis."

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"H1975 and H1650 transfected with si-USP8 showed a dramatic decrease in cell viability compared to mock transfected cells, indicating that the suppression of USP8 effectively decreases NSCLC cell viability (XREF_FIG and XREF_SUPPLEMENTARY)."

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Statements

USP8 activates Cell Survival. 3 / 3

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