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USP45 inhibits pH reduction. 2 / 2

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"Further, we showed that depletion of dUsp45/USP45 promotes V-ATPase localization to autolysosomes, thereby enhancing lysosomal acidification and autophagic–lysosomal activity."

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"dUsp45/USP45 impairs lysosomal acidification and disrupts the localization of V-ATPases to lysosomes by modulating actin structures."

40067150

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IndraLab

Statements

USP45 inhibits pH reduction. 2 / 2

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