IndraLab

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MIR21 activates YOD1. 2 / 2
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"In coxsackie virus B3 (CVB3)-infected myocarditis, the expression of miR-21 that targeted the mRNA of the deubiquitinase YOD1 was up-regulated, resulting in the downregulation of YOD1."

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"Furthermore, infection by the enterovirus coxsackievirus B3 (CVB3) leads to cardiac failure by inducing miR-21 expression, which targets the deubiquitinating enzyme YOD1."