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Mutated TP53 activates TP53-R270H. 1 / 1
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"Consistently, we found that decreased expression of mutant p53 by FDXR deficiency inhibited mutant p53 R270H to induce carcinoma and high grade pleomorphic sarcoma in FDXR +/-; p53R270H/- mice as compared with p53R270H/- mice."