IndraLab

Statements


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"Examples of inflammatory pathways include the TLR/NLRP3 pathway, where melatonin upregulates Nrf2 to inhibit NF-kb signaling, inhibiting NLRP3 and cytokine release (139, 140).6 Conclusion."

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"Melatonin has been shown to inhibit NFkB activation and help to inhibit NLRP3 inflammasomes, which are linked to lung disease induced by infections."

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"Because melatonin reduces constitutive NFKB activation in cultured pineal glands, we propose that this indolamine regulates this transcription factor pathway in the rat pineal gland, but not at the LD transition."

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"Our results show that melatonin reduces the cytokines TNF-α, IL-6, IL-1β, and NFkB."

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"* Melatonin : Melatonin has been shown to inhibit NFkB activation and NLRP3 inflammasome activation."