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PR-619 activates USP48. 2 / 2

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"Additionally, USP48 cleavage was observed in AML cells treated with chemotherapy drugs HHT (Figure 1f) and Ara-C (Figure 1g), and during ATRA-induced differentiation in NB4 cells (Figure 1h), indicating that both PR-619 and chemotherapy drugs induce USP48 cleavage in AML."

39878157

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reach

"We hypothesized that PR-619 and chemotherapy drugs induce USP48 cleavage through activated caspase-3."

39878157

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PR-619 activates USP48. 2 / 2

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