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Statements


Mice inhibits USP2. 2 / 2
| 2

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"Consistently, both immunohistochemistry and immunoblotting analyses showed that UCP1 abundance was lower in Usp2 knockdown mice compared to controls, which was rebounded by overexpression of EBF2 (Figure 7E,F)."

reach
"Of note, overexpression of EBF2 in BAT-specific USP2 knockdown mice not only reduced lipid droplet accumulation but also restored BAT mass, indicating that the dual effects of USP2 in BAT are at least partially mediated through the regulation of EBF2."