IndraLab

Statements

BAP1 inhibits Genomic Instability. 6 / 6
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"Specifically, BAP1 suppresses genome instability via its DNA repair activity and eliminates cancer-prone cells that exhibit genome instability by promoting apoptosis."
37009801
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"Here, we were particularly interested in potential roles of BAP1 in controlling mitotic progression and chromosome segregation and hence how loss of BAP1 contributes to genome instability."
36550359
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"BAP1 loss induces BRCA1 dependent and independent defective spindle organization, checkpoint dysfunction and genomic instability."
30405205
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"This indicates that BAP1 loss did not significantly augment genomic instability in our BNC mouse model."
32271879
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"The loss of BAP1 leads to genomic instability, which contribute to chronic pancreatitis and predisposes to cancer development11."
40083694
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"Loss of Bap1 causes genomic instability."
32541668