IndraLab

Statements

Arsenous acid decreases the amount of KCNH2. 11 / 11
6 | 5
ctd
No evidence text available
22853924
ctd
No evidence text available
28521025
ctd
No evidence text available
22977528
ctd
No evidence text available
25395240
reach
"Both arsenic trioxide (ATO) and angiotensin II (Ang II) were able to significantly reduce HERG protein expression, while also increasing PML SUMOylation and accelerating the formation of PML-NBs."
28525371
reach
"Ficker et al. (2004) demonstrated that arsenic trioxide did not show any direct inhibitory effect on hERG channel activity, whereas long-term exposure of hERG-expressing cell lines and ventricular myo[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
24998878
ctd
No evidence text available
25107562
ctd
No evidence text available
28768059
reach
"cardiac glycosides, arsenic trioxide, pentamidine, and ketoconazole) ( Ficker et al., 2004; Kuryshev et al., 2005; Takemasa et al., 2008; Wang et al., 2007 ) reduced hERG membrane expression by inhibi[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
27575519
reach
"cardiac glycosides, arsenic trioxide, pentamidine, probucol and ketoconazole) ( Wang et al., 2007; Ficker et al., 2004; Kuryshev et al., 2005; Guo et al., 2007; Takemasa et al., 2008 ) reduce hERG sur[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
20951697
reach
"Unlike other drugs that prolong the QT interval by blocking the cardiac I Kr channel, arsenic trioxide is claimed to block the expression of the I Kr protein (hERG) in cardiac cells."
23507039