IndraLab

Statements


WP1130 activates USP24. 3 / 3
| 3

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"In our study, using CETSA we have shown that WP1130 can direct target USP24 in T-ALL cells."

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"The partly specific DUB inhibitor WP1130 (Degrasyn) is able to inhibit activity of several DUBs including USP5, USP9x, USP14 and USP24 ( Kapuria et al., 2010 ; Luo et al., 2019 )."

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"In response to WP1130 treatment, USP24 was upregulated and acted as a compensatory mechanism for USP9x inhibition by WP1130."