IndraLab

Statements

BRCC3 activates IL1B. 4 / 4
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"Besides, inhibition of BRCC3 blocked the increased secretion of IL-1beta."
31787240
reach
"Since transduction of wild-type BRCC3, but not of the inactive mutant BRCC3 H122Q, rescued caspase-1 cleavage and IL-1beta secretion inhibited by BRCC3 KD, we conclude that BRCC3 regulates NLRP3 throu[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
23246432
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"Particularly, Benedicte et al. found that, knockdown of BRCC3 (a component of the BRISC complex) completely inhibited caspase-1 cleavage and IL-1beta secretion."
33627128
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"Furthermore, BRCC3 knockdown was shown to reduce the ATP induced secretion of mature IL-1beta by in macrophages."
33603747