IndraLab

Statements

CD4 binds CSF2 and ITGAM. 2 / 2
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"Our data suggest that the accumulation of GM-CSF-producing CD11b + CD4 + T cells is associated with disease progression in EAE, and that early anti-VLA-4 mAb therapy can prevent the accumulation of GM-CSF + CD11b + CD4 + T cells in the CNS by administration early in the course of disease progression."
24896098
sparser
"Taken together, these data support the early use of anti-VLA-4 mAb treatment to induce neuroprotection in progressive forms of CNS autoimmune disease by blocking the accumulation of GM-CSF-producing CD11b + CD4 + T cells in the CNS."
24896098