IndraLab

Statements

USP6 activates Interferon. 3 / 3
| 3
reach
"USP6 synergistically enhanced chemokine production in response to exogenous IFN by inducing surface upregulation of IFNAR1 and IFNGR1."
33558334
reach
"Single gene complementation of two Cluster V mutants, Tn : : Rv0712 and Tn : : hrp1 (hypoxic response protein 1, Rv2626c), restored the type I IFN response (XREF_FIG), suggesting that each of these genes is required for induction of type I IFNs."
28505176
reach
"Not only does USP6 independently induce activation of the IFN signaling mediators JAK1 and STAT1, but it also renders ES cells exquisitely responsive to exogenous IFNs, potentiating activation of STAT1 and STAT3."
30131449