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USP48 activates corticotropin secretion. 1 / 1

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"In this respect, further studies investigating the roles of USPs in UPS are required.Hyperactive mutations of Usp8 and Usp48 cause excessive ACTH secretion from corticotroph adenomas, implying that USP8 and 48 have the potential to modulate the hypothalamus-pituitary-adrenal axis under physiological conditions."

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USP48 activates corticotropin secretion. 1 / 1

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