IndraLab

Statements

BAP1 inhibits S phase. 4 / 4
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"Further cell cycle analysis revealed that overexpression of BAP1 in HCCC9810 cells significantly reduced cells in the S phase and arrested cells in the G0/G1 phase, which suggested that overexpression of BAP1 resulted in decreased G1-phase to S-phase cell cycle progression."
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"Silencing BAP1 could cause retarded cell proliferation in multiple mesothelioma cell lines through arresting S-phase of cell cycle, which was remitted by reintroducing BAP1 [13] ."
29787736
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"Although paradoxical for a tumor suppressor gene and contrary to in vivo observations, these data are consistent across cell lines of different origin [31,32] , suggesting that BAP1 suppression causes[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
32892058
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"BAP1 regulates replication fork formation, disrupts S phase arrest, and maintains G1max S phase fidelity under normal cellular conditions [29]."
39034372