IndraLab

Statements

Thymoquinone inhibits NLRP3. 5 / 5
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"These results indicate that TQ downregulated caspase-1 and NLRP3 in the CLP group mice."
32626733
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"Since the current study showed that TQ significantly inhibited NLRP3 in BC, it would be beneficial to investigate the impact of TQ/cyclin D on CDK4/6 in combination with Abemaciclib in BC, as it might provide a synergistic effect.To date, no clinical trials have investigated the effect of TQ on cancer in general or BC patients in particular."
37762557
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"A previous study [31] demonstrated that TQ significantly inhibits NLRP3, IL-1β, and IL-18 expression in CLP-induced septic cardiac damage."
37568105
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"The present study showed that TQ inhibited NLRP3 complex components in BC, which came in accordance with the aforementioned studies [101,102,103,104,105,106]."
37762557
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"However, the present study showed, for the first time, that TQ was a successful inhibitor to the danger signal CALR, NLRP3 and its downstream components."
37762557