IndraLab

Statements

USP20 binds HMGCR. 4 / 4
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"HMGCR recruited phosphorylated USP20 to form the HMGCR-USP20 complex, which protected HMGCR from proteasome-mediated degradation [177]."
36755301
sparser
"HMGCR recruited phosphorylated USP20 to form the HMGCR-USP20 complex, which protected HMGCR from proteasome-mediated degradation [ xref ]."
36755301
sparser
"By doing so, mTORC1 enhanced the USP20-HMGCR interaction and prevented HMGCR degradation."
37770289
sparser
"Furthermore, Lu XY et al. reported that mTORC1 might control cholesterol synthesis by regulating the USP20-HMGCR axis [53] , emphasizing the importance of mTORC1 activation."
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