IndraLab

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USP18 decreases the amount of IL2. 2 / 2

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"These data demonstrate that USP18 inhibits IL-2 expression and T cell proliferation in T cells after TCR stimulation as well as under Th17 polarizing conditions."

23825189

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"After TCR stimulation, USP18-deficient T cells display hyperactivation of NF-κB, JNK, and NFAT and produce increased level of IL-2."

31078284

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IndraLab

Statements

USP18 decreases the amount of IL2. 2 / 2

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