IndraLab

Statements


GRL0617 inhibits USP18. 2 / 2
| 2

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"Importantly, GRL0617 was unable to inhibit HAUSP, USP18, UCH-L1, UCH-L3, and a papain-like protease (PLP2) from the human coronavirus NL63."

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"To test whether GRL0617 can inhibit mouse deISGylating enzyme USP18, its activity was assayed in the presence of an inhibitor with 250nM ISG15-AMC (Boston Biochem) as substrate (excitation : 340nm; emission : 450nm)."