IndraLab

Statements


USP13 activates MYC. 2 / 2
| 2

reach
"In addition, IHC staining of Ki-67 and cleaved caspase 3 confirmed that USP13 disruption reduced c-Myc protein in the GSC derived xenografts and led to a significant decrease in cell proliferation and an increase in cell apoptosis within the tumor (not depicted)."

reach
"CHX chase assays indicated that overexpression of WT-USP13, particularly a phosphomimetic USP13-Y708E, but not USP-Y708F, significantly up-regulated the half-time of the c-Myc protein in HEK293 cells (XREF_FIG)."