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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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USP14 inhibits Interferon. 3 / 3

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"USP14 specific inhibitor, IU1, was demonstrated to increase RIG-I-mediated type I IFN production and antiviral responses in vitro and in vivo."

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"USP14 knockdown significantly enhanced RIG-I-triggered type I IFN signaling and inhibited VSV replication both in mouse peritoneal macrophages and THP1 cells."

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"Besides, USP14 specific inhibitor-IU1 increased RIG-I-mediated type I IFN production and antiviral responses in vitro and in vivo."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

USP14 inhibits Interferon. 3 / 3

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