IndraLab

Statements


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"USP14 specific inhibitor, IU1, was demonstrated to increase RIG-I-mediated type I IFN production and antiviral responses in vitro and in vivo."

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"USP14 knockdown significantly enhanced RIG-I-triggered type I IFN signaling and inhibited VSV replication both in mouse peritoneal macrophages and THP1 cells."

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"Besides, USP14 specific inhibitor-IU1 increased RIG-I-mediated type I IFN production and antiviral responses in vitro and in vivo."