
IndraLab
Statements
USP14 inhibits Interferon. 3 / 3
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3
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"USP14 specific inhibitor, IU1, was demonstrated to increase RIG-I-mediated type I IFN production and antiviral responses in vitro and in vivo."
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"USP14 knockdown significantly enhanced RIG-I-triggered type I IFN signaling and inhibited VSV replication both in mouse peritoneal macrophages and THP1 cells."
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"Besides, USP14 specific inhibitor-IU1 increased RIG-I-mediated type I IFN production and antiviral responses in vitro and in vivo."