IndraLab

Statements

Olmesartan inhibits MAP3K7. 4 / 4
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"Moreover, Olmesartan reduced the level of transforming growth factor beta activated kinase-1 (TAK1) and phospho-p38MAPK."
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"We may partially demonstrate the beneficial role of Olmesartan on patients with late-stage heart failure although we did not compare the role of Olmesartan and that of other sartans in the overload-pr[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"In neonatal rat cardiac fibroblast cells and cardiomyocytes, Olmesartan also decreased TAK1 and p38MAPK activation triggered by TGFbeta1 or AngII."
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"Taken together, our data suggested Olmesartan reduced phosphor-TAK1 and p38, which is involved in cardiac apoptosis and remodeling in the setting of stress."
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