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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

STAT3 activates USP25. 1 / 1

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"Moreover, the expression of exogenous STAT3 effectively activated USP21 promoter driven luciferase expression in a dose dependent manner (XREF_FIG), whereas mutating the core STAT3 binding sequence (TGCTTCCCC to TGCCCACCC) within the USP21 promoter abolished the effect of STAT3 (XREF_FIG)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...