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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

SIRT1 activates COPS5. 1 / 1

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"The involvement of the deacetylase activity of Sirt1 was confirmed by the ability of its pharmacological inhibitors, nicotinamide (50 mM) and splitomicin (200 microM), to rescue Csn5, Skp2 and beta-TrCP from CG-12-induced changes to their expression levels (XREF_FIG)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...