IndraLab

Statements

2-(2-amino-3-methoxyphenyl)chromen-4-one inhibits FOS. 5 / 7
| 4 1
reach
"Further, neither PD 98059 nor wortmannin could block the upregulation of c-fos when co-treated with G1 and G15 ( Fig 3 C)."
22554835
reach
"Interestingly, G15 induced c-fos upregulation was inhibited by both PD 98059 and wortmannin which is similar to that of E2 ( Fig 3 D)."
22554835
reach
"The role of the ERK signaling cascade in gene regulation was confirmed after intrastriatal and unilateral injection of the specific ERK inhibitor PD 98059, which completely abolished c-fos, zif 268, and MKP-1 mRNA induction in the injected side."
9786988
sparser
"These results contrasted with hormone-dependent activation of the SRE in the c-fos promoter, which was inhibited by both PD98059 and LY294002."
15449318
reach
"In S9 cells, PD-98059 suppressed c-Fos upregulation by OD10 supernatant, Hla, or Hlb, indicating that c-Fos expression requires activation of Erk-type MAP kinases."
19098123