IndraLab

Statements


PSMD14 activates TP53. 3 / 3
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"POH1 Knockdown Attenuates Degradation of p53 and Bim."

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"Knockdown of POH1 dramatically attenuated the degradation of p53 and Bim in QGY-7701 (XREF_FIG A), EC109 (XREF_FIG B), and HCT116 (XREF_FIG C) cells."

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"Although it may seem a bit contradictory, we demonstrate that knockdown of POH1 (a deubiquitining enzyme) could diminish the ubiquitin modification of p53 and Bim, and we speculated there were some reasons."