IndraLab

Statements

TNFAIP3 inhibits Ubiquitin. 3 / 3
| 3
reach
"TNFAIP3 inhibits NF-kappaB activation by exerting dual ubiquitin editing functions [XREF_BIBR]."
28152507
reach
"CYLD and TNFAIP3 and A20 negatively regulate the NFkappaB pathway by removing ubiquitin chains from multiple signaling molecules including TRAFs and RIP."
19615732
reach
"Ubiquitin-editing enzyme TNFAIP3 is able to abolish NF-κB activation by removing ubiquitin chains from key components of TNFR signaling pathway (such as RIP1 and NEMO) that leads to their proteasomal degradation; notably, SNPs in TNFAIP3 are associated with CD [49]."
32610492