IndraLab

Statements



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"Collectively the data suggest that chronic peripheral (non lymphoid tissue) sites of antigen deposition are detrimental to the development and/or maintenance of immune memory while SLO sites of antigen promote protective memory by modulating the differentiation status of the circulating memory pool."

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"The SLO data also support our earlier hypothesis that monocytes must undergo maturation and differentiation in the circulation before they acquire the ability to roll on inflamed endothelium and that changes in monocyte receptor function are crucial events that enable inflammatory monocytes to traffic to the site of inflammation."