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GW 501516 inhibits NFKB1. 2 / 2

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"GW501516 reduced Nfkb1 activity in control cells, but not when Pparb or Bcl6 were knocked down, indicating the potential repressive mechanism is dependent on both proteins."

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"In control cells, GW501516 reduced both basal and TNFalpha stimulated Nfkb1 luciferase activity, as well as slightly elevating basal activity though not significant."

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IndraLab

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GW 501516 inhibits NFKB1. 2 / 2

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