IndraLab

Statements


Hypoxia increases the amount of USP13. 2 / 2
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"In HCC, hypoxia induces USP13 expression, enhancing TLR4 deubiquitination and activating the TLR4/MyD88/NF‐κB pathway, which accelerates tumour growth [18]."

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"By contrast, USP13 expression induced by hypoxia activates TLR4/MYD88/NF-κB signaling and promotes cell proliferation (81)."