IndraLab

Statements

USP12 inhibits cell population proliferation. 7 / 9
| 7
reach
"As shown in XREF_FIG B, knockdown of WDR48 and USP12 by shRNA accelerated the rate of cell proliferation compared with control shRNA transfected cells."
24145035
reach
"In contrast, overexpression of WDR48 and USP12 (XREF_FIG C) suppressed cell proliferation similarly to PHLPP1 (XREF_FIG D)."
24145035
reach
"We further established that Usp12 depletion reduced PC cell proliferation and induced apoptosis, furthermore Usp12 levels are increased in PC tissue [XREF_BIBR]."
26462181
reach
"Over-expression of USP12 induced apoptosis and suppressed the proliferation of HCT116 cells ( Gangula and Maddika, 2013 )."
26680102
reach
"Several studies reported the effects of USP12 on cell phenotypes, and we give a summary of the roles and mechanisms of USP12 in tumorigenesis in the following part.The overexpression of USP12 in human colorectal cancer cells was previously found to inhibit cell proliferation, and siUSP12 could reverse this effect [63]."
37752518
reach
"Furthermore, PI staining by flow cytometry analysis revealed that USP12 deletion significantly increased G0/G1 phase cell proliferation (Fig. 2H–K)."
38605077
reach
"As a result, depleting Usp12 decreased PC cellular proliferation and increased cellular apoptosis suggesting it may be a potential target for CRPC therapy [XREF_BIBR]."
25216524