IndraLab

Statements

USP11 inhibits USP11. 2 / 2
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"This provides us a new perspective for future studies.In conclusion, in our present study, we found that IsoLiPro can lower USP11 protein levels both in vivo and in vitro, mainly through modulating protein degradation without impacting directly the USP11 enzyme activity, and consequently ameliorate AD pathologies in transgenic AD animal model."
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"Furthermore, there is a rapid loss of USP11 upon DNA damage induction, specifically in G1 phase (XREF_FIG and XREF_FIG)."
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