IndraLab

Statements

ATM binds USP34. 9 / 9
2 | 2 5
sparser
"We found the possible binding of USP34 with ATM, which was further testified with co-IP ( Fig. 4 B)."
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sparser
"Mechanically, USP34 interacts with ATM to inhibit the expression of Ccl2, Ccl5, and Il12α in LPS-stimulated BMDMs."
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biogrid
No evidence text available
17478428
biogrid
No evidence text available
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sparser
"Such inflammation inhibition may be attributed to the interaction between USP34 and ataxia telangiectasia-mutated (ATM)."
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reach
"Immunoprecipitation demonstrated the interaction between USP34 and ATM."
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reach
"USP34 deficiency in macrophages promotes the onset of vitiligo with increased PMEL CD8 + T cell enrichment, and USP34/ATM complex can be considered as a therapy target."
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sparser
"In our study, we hypothesize that USP34 can interact with ATM, and USP34 may function as a ubiquitin hydrolase to maintain the stability of ATM."
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sparser
"It is worth noting that the precise mechanism related to the interaction between USP34 and ATM is not deciphered in this study, which will require further analysis."
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