IndraLab
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"These included genes such as chemokines CXCL1 , CXCL10 and CXCL8 and genes associated with autoimmune diseases such as HLA-C , DDX58 , IL4 , NFKBIA and TNFAIP3 which are associated with psoriasis susceptibility.[ xref ] Moreover, NFKB1 from this module mediates Th1/Th17 activation in the pathogenesis of psoriasis and probably other autoimmune diseases.[ xref ] Green genes also had more DMRs, either in the gene bodies or in GH elements mapped to the genes, suggesting that TNFa stimulation causes more long-lasting changes to gene expression to genes in the green set than to other sets."