IndraLab

Statements


COPS5 inhibits COPS5. 3 / 3
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"In CSN5 knockdowns c-Jun destabilization was rescued by CSN5 overexpression, demonstrating the substrate receptor role of CSN5."

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"We next examined whether suppression of Jab1 expression could increase the sensitivity of NPC cells to cisplatin, IR and UV by knocking down Jab1 in HONE1 and CNE2 cells."

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"Supporting CSN5 specific inhibition on mRNA levels (XREF_FIG), we found a significant reduction only in CSN5 protein levels while other CSN subunits (e.g. CSN1, CSN3 and CSN8) showed little or no change (XREF_FIG)."