IndraLab

Statements

KCNA5 inhibits apoptotic process. 5 / 8
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"Silencing Kv1.5 expression in the osteosarcoma cells significantly inhibited the proliferation of osteosarcoma cells, induced cell cycle arrest at G0/G1 phase, and induced cell apoptosis through up-regulation of p21, p27, Bax, Bcl-XL and caspase-3 and down-regulation of cyclins A, cyclins D1, cyclins E, Bcl-2 and Bik."
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"Silencing of Kv1.5 Gene Inhibits Proliferation and Induces Apoptosis of Osteosarcoma Cells."
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"In vitro , miRNA153 increased the level of Kv1.5 in hypoxic PASMCs by targeting NFATc3 and inhibiting their proliferation and apoptosis resistance."
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"KV1.5 overexpression in rat PASMCs decreased apoptosis resistance by increasing caspase-3 activity [113] ."
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"In contrast, overexpression of KCNA5 gene or attenuation of Kv1.5 downregulation XREF_BIBR, XREF_BIBR, XREF_BIBR reduces apoptosis during these diseases."
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