IndraLab

Statements

Nickel(2+) inhibits IRF7. 3 / 3

| 3

➶

reach

"Nickel decreased interferon regulatory factor (IRF) 3 and IRF7, IKKepsilon, and Sp100."

21466819

➶

reach

"The present study demonstrated that nickel decreased interferon regulatory proteins IRF3 and IRF7, and activated NF- kappaB, resulting in DeltaNp63 suppression and then p21 up-regulation."

21466819

➶

reach

"In summary, our results showed that in keratinocytes nickel is able to decrease IRF3 and IRF7, and then activate NF-kappaB."

21466819

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

Nickel(2+) inhibits IRF7. 3 / 3

INDRA sources:

Databases

Reading