IndraLab

Statements

SPP1 binds CD4. 2 / 2
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"The authors hypothesized that several stressors arrest the cell cycle, and macrophages exposed to severe damage undergo senescence and produce the SASP factors IL-6 and CXCL9 upon interaction with CD4 + osteopontin (OPN) + CD153 + senescent T cells."
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"Studies have also shown that the absence of OPN is associated with B-cell abnormalities including the generation of memory B-cells and their persistence as early as primary HIV or SIV infection ; decr[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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