IndraLab

Statements

BAP1 activates Neoplasm Invasiveness. 5 / 5
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"Loss of BAP1 reduces immune cell infiltration and accelerates B cell lymphoma growth in vivo.."
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"We then investigated whether and how BAP1 modulates T lymphocyte infiltration in MPM."
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"Loss of BAP1 leads to a dramatic reduction of MHC-II gene expression and reduced immune cell infiltration in animal models, resulting in a substantial acceleration of tumor growth."
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"Lack of BAP1 increased the production of chemokines to attract T-cell aggregation, resulting in greater T-cell infiltration, a negative prognostic factor according to Broggi, G et al. [18]."
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"Mutations in BAP1, which were the most frequent in CCRCC among all cancers (Figure 3A), were suggested to be pathogenic and promote CD8 T cell infiltration in CCRCC."
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